Esketamine, offered at Retreat, expands options for treatment-resistant depression

The Keene Sentinel

Recently, Dr. Lance Thigpen administered esketamine treatment to a man who said he had experienced near-constant suicidal thoughts for 30 years.

Within 90 minutes, the man, who the Brattleboro Retreat declined to identify because of privacy concerns, told Thigpen his thoughts of suicide were gone. The patient has now been in care for about six weeks, and hasn’t experienced the return of his suicidal thoughts, Thigpen said.

It was a remarkable transformation, Thigpen said, but one that wasn’t wholly unexpected for the psychiatrist and director of outpatient services at the Retreat, a mental health and substance use disorder treatment facility.

“It is a miracle for some people,” he said.

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